SEROPREVALENCE OF HEPATITIS B AND C – REPORT OF A PUBLIC HEALTH OUTREACH IN SOUTH-WEST NIGERIA BY THE ENLIGHTENMENT INITIATIVE ON VIRAL HEPATITIS

Authors

  • Oluwatosin Oguntoye O Enlightenment Initiative on Viral Hepatitis, Ede, 232101 Osun State, Nigeria. https://orcid.org/0000-0002-5573-3717
  • Ariyo Olumuyiwa E Department of Medicine, Federal Teaching Hospital Ido-Ekiti, 371101 Ekiti State, Nigeria.
  • Abdulkareem Lukman Department of Internal Medicine, University of Abuja Teaching Hospital Gwagwalada, 902101 Abuja, FCT, Nigeria
  • Osasona Oluwadamilola G Department of Medical Laboratory Sciences, Faculty of Basic Sciences, Redeemers University Ede, 232101 Osun State, Nigeria
  • Ifeorah Ijeoma M Center for Translation and Implementation Research, College of Medicine, University of Nigeria, 410001 Enugu State, Nigeria.
  • Eromon Philomena E African Centre of Excellence for Genomics of Infectious Diseases, Redeemers University Ede, 232101 Osun State, Nigeria.
  • Chukwurah Ifeanyi Marketing Department, Fidson Healthcare Plc., Obanikoro, 100232 Lagos State, Nigeria.
  • Oguntoye Oluwafunmilayo A Department of Medicine, Afe Babalola University Ado-Ekiti, 360001 Ekiti State, Nigeria https://orcid.org/0000-0001-9893-2073
  • Nkereuwem Precious E Department of Medicine, Afe Babalola University Ado-Ekiti, 360001 Ekiti State, Nigeria

DOI:

https://doi.org/10.37268/mjphm/vol.23/no.2/art.2064

Keywords:

Hepatitis B, Hepatitis C, Liver Disease, Prevalence, Population, Nigeria

Abstract

Hepatitis B virus infection is the commonest cause of chronic liver disease in Nigeria with its attendant complications. Majority of Nigerians do not know their status, therefore there is a need to routinely screen the populace to detect those who are infected. The objective of this study is to determine the prevalence of Hepatitis B and C among the participants of a public health outreach. This was an observational cross-sectional study conducted by the Enlightenment Initiative on Viral Hepatitis during the 2022 World Hepatitis Day. Consenting patients attending the General Out-Patient Clinic of the hospital were counselled and screened for HBsAg and Anti-HCV using Rapid Test Kits. Consenting members of staff of the hospital were also counselled and screened. A total number of 171 patients participated in the free screening exercise; 53 males (31%) and 118 females (69%) with a mean(±SD) age of 37.27±13.65. Seventy-five members of staff of the hospital also participated in the free screening exercise; 29 males (38.7%) and 46 females (61.3%) with a mean(±SD) age of 43.36±6.48. All the 171 patients were screened for HBsAg and 7(4.1%) were found to be reactive. Similarly, all the 75 members of staff were screened for HBsAg and 1 (1.3%) was found to be reactive. Furthermore, 50 of the patients were screened for anti-HCV and 3(6.0%) of them were found to be reactive. Hepatitis B and C viruses are very much prevalent in our environment. The importance of routine screening for these viruses in our population cannot be overemphasized

References

Pyrsopoulos NT. Hepatitis B. Available at: https://emedicine.medscape.com/article/177632-overview. Published 2022. Accessed 2023.

World Health Organization. Hepatitis B. Available at:

https://www.who.int/news-room/fact-sheets/detail/hepatitis-b. Published 2022. Accessed 2023.

World Health Organization. Global progress report on HIV, viral hepatitis and sexually transmitted infections. Available at:

https://www.who.int/publications/i/item/9789240027077. Published 2021. Accessed 2023.

World Health Organization. Global health sector strategy on viral hepatitis 2016–2021: Towards ending viral hepatitis. Available at: https://apps.who.int/iris/bitstream/handle/10665/246177/WHO-HIV-2016.06-eng.pdf. Published 2016. Accessed 2023.

Malu AO, Ajayi AO, Okeke EN, et al. Guidelines for the management of chronic Hepatitis B and C. Nigerian Journal of Gastroenterology and Hepatology. 2021;13(1):1-23.

Musa BM, Bussell S, Borodo MM, et al. Prevalence of hepatitis B virus infection in Nigeria, 2000-2013: a systematic review and meta-analysis. Niger J Clin Pract. 2015;18(2):163-72. doi: 10.4103/1119-3077.151035.

Ajuwon BI, Yujuico I, Roper K, et al. Hepatitis B virus infection in Nigeria: a systematic review and meta-analysis of data published between 2010 and 2019. BMC Infectious Diseases. 2021;21(1120):1-15. doi:10.1186/s12879-021-06800-6.

World Health Organization. Hepatitis C. Available at: https://www.who.int/news-room/fact-sheets/detail/hepatitis-c. Published 2022. Accessed 2023.

Federal Ministry of Health. ‘National guidelines for the prevention, care and treatment of viral hepatitis B and C in Nigeria’. Available at: https://www.hepb.org/assets/Uploads/Nigeria-Hepatitis-Guidelines-TX-guidelines.pdf. Published 2016. Accessed 2023.

Olayinka AT, Oyemakinde A, Balogun MS, et al. Seroprevalence of Hepatitis B Infection in Nigeria: A National Survey. Am. J. Trop. Med. Hyg. 2016;95(4):902–907. doi:10.4269/ajtmh.15-0874.

Berinyuy BE, Alawode RA, Mohammed AB, et al. Prevalence of Hepatitis B Virus in Nigeria: Review Update. Annal Pub Health & Epidemiol., 2019;1(1):1-7. doi:10.33552/APHE.2019.01.000501.

Enlightenment Initiative on Viral Hepatitis. About Us. Available at: https:// eivh.org. Published 2022. Accessed 2023.

Olasehinde N. Healthcare seeking behaviour in Nigeria. Journal of Population and Social Studies. 2018;26(3):207-218. doi: 10.25133/JPSSv26n3.015.

Thompson AE, Anisimowicz Y, Miedema B et al. The influence of gender and other patient characteristics on health care-seeking behaviour: a QUALICOPC study. BMC Fam Pract. 2016 17, 38 doi: 10.1186/s12875-016-0440-0.

Atlaw D, Sahiledengle B, Tariku Z. Hepatitis B and C virus infection among healthcare workers in Africa: a systematic review and meta-analysis. Environmental Health and Preventive Medicine. 2021;26(61):1-14. doi:10.1186/s12199-021-00983-9.

Gomaa AI, Khan SA, Toledana MB, et al. Hepatocellular carcinoma: epidemiology, risk factors and pathogenesis. World J Gastroenterol. 2008;14:4300 – 4308. doi: 10.3748/wjg.14.4300.

Ndububa D, Ojo O, Lesi O, et al. Management of Hepatocellular carcinoma. Nigerian Journal of Gastroenterology and Hepatology. 2015;7(2):77-92.

Ajayi BB, Ngadda HA, Moses AE. Hepatocellular carcinoma among patients diagnosed with and without hepatitis B surface antigenaemia in a Nigerian tertiary hospital. Microbiology Research. 2009;1:121 – 124.

Oguntoye OO, Yusuf M. An 8-year Retrospective Review of Gastrointestinal Medical Emergency Conditions at a Tertiary Health Facility in Nigeria. Sudan Journal of Medical Sciences, 2018;13(1):1-11. doi: 10.18502/sjms.v13i1.1684.

Oguntoye OO, Yusuf M, Olowoyo P, et al. Spectrum of Disease Conditions Seen at the Gastroenterology Clinic of a Tertiary Health Facility in South-Western Nigeria. Journal of Advances in Medicine and Medical Research. 2020;32(6):77-87. doi:10.9734/JAMMR/2020/v32i630437.

World Health Organization. Combating Hepatitis B and C to Reach Elimination by 2030. Available at: https://www.who.int/publications/i/item/combating-hepatitis-b-and-c-to-reach-elimination-by-2030. Published 2016. Accessed 2023

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Published

2023-08-28

How to Cite

Oguntoye O, O., Ariyo, O., Abdulkareem, L., Osasona, O., Ifeorah, I., Eromon, P., … Nkereuwem, P. (2023). SEROPREVALENCE OF HEPATITIS B AND C – REPORT OF A PUBLIC HEALTH OUTREACH IN SOUTH-WEST NIGERIA BY THE ENLIGHTENMENT INITIATIVE ON VIRAL HEPATITIS. Malaysian Journal of Public Health Medicine, 23(2), 198–204. https://doi.org/10.37268/mjphm/vol.23/no.2/art.2064